Start with the work, not the plan name
For an IT team looking after 100 to 300 people, the useful question is which rights and controls each group needs. Document the apps, Windows requirements, device management, email protection and compliance work you actually operate. Then compare the complete licence package, including any add-ons needed to retain those capabilities.
This guide compares Microsoft 365 E3, not Office 365 E3. They are different bundles. An invoice that says only 'E3' is not enough to confirm the product. Use our Microsoft 365 E3 page for the exact product and a quote request.